Pharmacist

Cialis

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Cialis (tadalafil) is a PDE-5 inhibitor, which is actively used to treat erectile dysfunction and impotence in men.

How does it work?

Tadalafil-based potency regulators increase blood flow to the male genitalia, contributing to the appearance or strengthening of a natural erection. An erection occurs 40-45 minutes after taking the pill (only if a man is sexually aroused). Thanks to the action of tadalafil, a man is provided with a record activity duration of 36 hours. This means that after taking this drug, you and your partner can enjoy high-quality sex for 1.5 days with the possibility of repeated intercourse after the next ejaculation.

Dosage and administration

Tadalafil is rapidly absorbed from the gastrointestinal tract and starts working after 40-50 minutes. The maximum amount of tadalafil in blood plasma is reached after 2 hours. Therapeutic doses of tadalafil can vary from 5 mg to 20 mg, depending on the diagnosis, dosage regimen, effectiveness, safety, limitations and other reasons. The tablet can be divided or taken whole. Fatty foods and small doses of alcohol do not affect the pharmacokinetics of tadalafil and do not interact with it. Follow the dosing recommendations given by your doctor and the instructions in this manual. Do not use Cialis in larger or smaller amounts, as well as longer than indicated in the instructions and recommended by your doctor. The drug is active for up to 36 hours (depending on the individual characteristics of the patient). You cannot take the drug more often than once a day.

Overdose

An increase in the dosage of tadalafil increases the likelihood of adverse effects: headache, dizziness, decreased blood pressure, muscle pain, runny nose and others. As a rule, such effects are temporary, mild and do not require special medical intervention. In order to alleviate the patient’s condition and relieve the main symptoms, symptomatic therapy is usually recommended. If severe adverse effects occur, contact your doctor immediately.

Contraindications

Do not take Cialis pills in the following cases:

  • Hypersensitivity to tadalafil and other components that make up the generic.
  • Minors or men over 65 years of age
  • Severe diseases of the cardiovascular system (a recent stroke or heart attack, heart failure, arrhythmia, heart defects).
  • Diseases of the liver and kidneys in a severe stage.
  • Oncological pathologies.
  • If you have acute or chronic diseases, do not take the drug without a consultation with a doctor who will determine the optimal dosage for your condition.

Interaction with other medicines

Using Cialis with certain medicines may be unsafe. Tell your healthcare provider about all medicines you take or will take with tadalafil, especially:

  • Drug nitrates that are usually prescribed for the relief of heart pain. Nitrates can also be found in some inhaled drugs called poppers;
  • Guanylate cyclase stimulants used to treat pulmonary arterial hypertension and chronic thromboembolic hypertension;
  • Alpha-blockers prescribed to treat arterial hypertension and prostatic hyperplasia;
  • Medications to treat blood pressure;
  • Medicines for the treatment of HIV / AIDS (ritonavir, saquinavir) or certain types of oral antifungal agents (ketoconazole, itraconazole);
  • Most antibiotics (clarithromycin, telithromycin, erythromycin, etc.);
  • Other drugs used in the treatment of erectile dysfunction (ED), especially PDE-5 inhibitors (vardenafil, sildenafil, etc.).

Special recommendations

Drugs with tadalafil can be taken for a long period of time as part of the complex treatment of ED, benign prostatic hyperplasia (BPH), BPH + ED. Tadalafil should be taken daily at a dosage of 5 mg. The period of admission is from 1 to 2 months. After a month, if necessary, such a regimen can be repeated. Do not attempt to compensate for missed dosages with additional doses of tadalafil. Drink the next dose as soon as the time comes for your next medication.

Men with pulmonary hypertension usually take a dosage of 40 mg. Tablets are taken at the same time, once a day.

Patients with moderate renal dysfunction can take only 10 mg/day.

The pharmacokinetics of tadalafil has not been studied in patients with hepatic insufficiency in dosages of more than 10 mg of tadalafil. A plasma concentration of 10 mg tadalafil for patients with mild to moderate hepatic impairment was comparable to that in healthy patients. Tadalafil has not been studied in severe liver failure (type C).

Plasma concentrations of tadalafil in patients with diabetes mellitus were on average 19% lower than in healthy people, which does not find any reason for increasing the dosage in clinical practice.

When taking Tadacip 20 with alcohol, reasonable drinking standards should be followed. Large amounts of alcohol consumed can cause a drop in blood pressure, which in turn can provoke headache, pale skin, orthostatic hypotension, dizziness, and fainting.

Advantages of Cialis

The benefits of this generic remedy include:

  • Safe composition and clinically proven effectiveness (an erection occurs even in severe forms of impotence, including hormonal disorders and diabetes mellitus);
  • Low price (this generic version costs much less than the branded Cialis);
  • Positive reviews from patients who have already tried these pills;
  • Ease of use and the possibility of regular use;
  • No drug dependence and the effect is not reduced over time;
  • A small number of contraindications and adverse reactions;
  • The compatibility with most other drugs to treat diseases;
  • Long-term effect (up to 36 hours);
  • Suitable for almost all adult men.