|100mcg||1inhaler||$36.99||$36.99 per inhaler|
|100mcg||3inhalers||$74.99||$25.00 per inhaler|
|100mcg||6inhalers||$163.99||$27.33 per inhaler|
Ventolin is a drug intended for the treatment of bronchial asthma. It contains albuterol. It expands narrowing bronchial lumens.
Ventolin (albuterol) is a selective β2-adrenergic receptor agonist. In therapeutic doses, this agent acts on β2-adrenergic receptors of the bronchial smooth muscles. It has a short-term (4 to 6 hours) bronchodilating effect on β2-adrenergic receptors with a rapid onset of action (within 5 min). It provides reversible airway obstruction.
It has a pronounced bronchodilating effect. It either prevents or stops bronchospasm. It also reduces resistance in the airways. It increases lung capacity and mucociliary clearance (in chronic bronchitis up to 36%). It stimulates mucus secretion, activates the ciliated epithelium functions.
In the recommended therapeutic doses, it does not adversely affect the cardiovascular system, does not cause an increase in blood pressure. To a lesser extent, in comparison with the medications of this group, it has a positive chronical and inotropic effect. It causes the expansion of the coronary arteries.
It has a number of metabolic effects: it reduces the concentration of potassium in the plasma, affects glycogenolysis and insulin secretion. It has a hyperglycemic (especially in patients with bronchial asthma) and a lipolytic effect. It increases the risk of acidosis.
- relief of bronchial asthma symptoms;
- prevention of bronchospasm attacks associated with exposure to an allergen or caused by physical exertion;
- use as one of the components for long-term maintenance therapy of bronchial asthma.
Other chronic lung diseases accompanied by reversible airway obstruction, including COPD, chronic bronchitis, emphysema.
Bronchodilators should not be the only or main component of therapy for unstable or severe bronchial asthma. In the absence of a reaction to salbutamol in patients with severe bronchial asthma, it is recommended to administer GCS therapy in order to achieve and maintain control over the disease. The lack of response to salbutamol therapy may indicate the need for urgent medical advice or treatment.
Ventolin is intended only for inhalation by inhalation through the mouth.
An increased need for the use of β2-adrenergic receptor agonists may be a sign of bronchial asthma exacerbation. In such a situation, a reassessment of the patient’s treatment regimen may be necessary with consideration of the advisability of prescribing concurrent therapy for corticosteroids.
Because an overdose can be accompanied by the development of adverse reactions, the dose or frequency of drug use can be increased only on the doctor’s recommendation.
The duration of albuterol action in most patients is from 4 to 6 hours.
In patients experiencing difficulty in synchronizing inhalation using a metered-dose aerosol inhaler, a spacer can be used.
In children and infants receiving Ventolin, it is advisable to use a pediatric spacer device with a face mask.
For stopping a bronchospasm attack in adults, the recommended dose is 100 or 200 mcg; children – 100 mcg. If necessary, the dose can be increased to 200 mcg. It is not recommended to use the Ventolin inhaler for over 4 times/day. The need for such frequent use of additional Ventolin doses or a sharp increase in dose indicates asthma exacerbation.
To prevent attacks of bronchospasm associated with exposure to an allergen or caused by physical exertion, adults should take 200 mcg 10-15 minutes before exposure to a provoking factor or load; children – 100 mcg for 10-15 minutes before exposure to a provoking factor or physical exercises. If necessary, the dose can be increased to 200 mcg.
With prolonged maintenance therapy: adults – up to 200 mcg 4 times/day; children – up to 200 mcg 4 times/day.
When using a Ventolin inhaler in high doses, patients may develop a blood pressure decrease, increased heart rate, vomiting, muscle tremors, and agitation. In severe cases, patients may develop cramps and hallucinations, respiratory alkalosis. The treatment is symptomatic. In order to alleviate the condition, the patient is administered the drugs included in the group of cardioselective beta-blockers.
Hypersensitivity to the drug or any other component is the main contraindication. Be cautious when taking albuterol if you have thyrotoxicosis, tachyarrhythmia, myocarditis, heart defects, aortic stenosis, coronary heart disease, severe chronic heart failure, arterial hypertension, pheochromocytoma, decompensated diabetes mellitus, glaucoma.
Hypersensitivity reactions are possible: angioedema, bronchospasm, urticaria, hypotension up to collapse. When using the drug, a decrease in the level of potassium in the blood plasma is possible. Headache, tremors, irritability, and hyperactivity may also occur.
Tachycardia often occurs, sometimes there is a violation of the heart rhythm: supraventricular tachycardia, extrasystole, atrial fibrillation. Ventolin may cause peripheral vasodilation.
When using this asthma inhaler, paradoxical bronchospasm may occur, with a significant increase in dyspnea after inhalation. In such cases, the drug is discontinued, alternative treatment methods are selected for the patient. With inhalation of Ventolin, irritation of the mucous membrane of the oral cavity and pharynx was sometimes observed. The drug can cause muscle cramps.
Pregnancy and breastfeeding
Ventolin inhaler can be used in the treatment of pregnant women in cases when the benefit to the mother overweighs the possible risk to the fetus. The drug use in the treatment of pregnant women is carried out only in extreme cases since there is information about the birth of infants with polydactyly in mothers who took Ventolin during pregnancy. The use of the drug during pregnancy is indicated in cases when a woman has a high risk of placental hypoxemia of the fetus. When prescribing an aerosol to pregnant women, it is necessary to remember that the use of albuterol can provoke hyperglycemia and tachycardia in the fetus and mother. Also, the systematic use of Ventolin can cause a weakening of labor, a pronounced decrease in blood pressure and pulmonary outflow.
- Ventolin and non-selective beta-blockers (propranolol) cannot be used in combination. With thyrotoxicosis, tachycardia is observed. It also enhances the effect of drugs that stimulate the central nervous system.
- It increases the likelihood of developing arrhythmias while taking cardiac glycosides.
- Ventolin is not contraindicated in patients who take MAO inhibitors.
- Theophylline and other xanthines when taken together with Ventolin increase the likelihood of tachyarrhythmias.
- When taken together with means for inhalation anesthesia and levodopa, ventricular arrhythmias may occur.
- Intraocular pressure may increase when Ventolin is taken together with anticholinergics.
- Glucocorticosteroids and diuretics can increase the hypokalemia caused by Ventolin.